Synergy Discussion

[Holylifton]

So I've read up on synergy but I can't seem to find anything that tells me how I'm supposed to know when and I should hit a particular mob with which ability in order to exploit a synergy opportunity. I know I've done it during the beta because I had to fill out a survey on the topic but quite frankly, I was just Forrest Gumping my synergy strikes. I didn't even know when I had successfully triggered a synergy. Does anyone have any insight to this aspect of the game?