It is upto the game developer to prevent "cheating."
If an addon can be done to partially automate the combat for example, it will be made by someone and it will be used by some.
Personally I do hope that they will restrict the API quite a bit so stuff like that can't be made.
I've not heard any harmful addons yet but I guess this is somehow related as one of the PTS testers have said:
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And don't get me started on the addon massacre, which was primarily information most MMORPG's put in their base UI such as hitpoint numbers and buff icons as options.
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http://forums.bethsoft.com/topic/149...d-not-crafted/